Aggregator

切断手術を行う際に、締め付けるための器具(止血帯)を使用することは、合併症の低減に対し有効かつ安全か?

1 year 10 months ago
切断手術を行う際に、締め付けるための器具(止血帯)を使用することは、合併症の低減に対し有効かつ安全か? 背景 毎年、世界で数百万人もの人々が動脈閉塞性疾患にかかり、切断手術を余儀なくされている。切断手術では大量の血液が失われ、死亡を含む合併症を引き起こす可能性がある。輸血にはリスクが伴うが、切断する脚の上部を圧迫する器具である止血帯の使用は、出血量を減らし、輸血の必要性を減らすことができる。これは膝関節に対し人工関節置換術を行う際には安全であると考えられているが、手術を受ける血管に閉塞性疾患がある場合への使用については、依然として議論の余地がある。また、止血帯により患者の皮膚、筋肉、および血管が損傷を受け、切断部への血液供給が減少することで、創傷治癒に影響を与える可能性についての懸念がある。 本レビューでは、血管の閉塞性疾患により切断手術が行われる場合の止血帯の使用が、手術中の失血量、血球数の低下、輸血の必要性や、創傷の治癒、再手術の必要性などの合併症の低減に安全かつ効果的であるかどうかを調査した研究について検索を行った。 研究の特徴および主な結果 血管の閉塞が原因で切断術を受ける患者において、止血帯を使用した場合と止血帯を使用しなかった場合とを比較した研究を探すため、医学データベースを検索した。その結果、英国で実施されたランダム化比較試験(患者を2種類以上のいずれかの治療群に無...

家族計画や避妊法の利用を支援するための、携帯電話を使って提供される介入

1 year 10 months ago
家族計画や避妊法の利用を支援するための、携帯電話を使って提供される介入 論点 このレビューの目的は、携帯電話による介入が避妊法の利用を増進するかどうかを判断することである。 要点 携帯電話による介入は、避妊法の増進と継続的な利用に良い影響をもたらす。 双方向性のメッセージは、避妊法の利用を増進する上で、一方的なテキストメッセージよりも優れている。 現存するエビデンスのレベルは中等度である。 このレビューの重要性 携帯電話で配信されるヘルスメッセージや介入は、健康や行動を改善することが示されているが、携帯電話で配信されるメッセージが、避妊の使用などリプロダクティブ・ヘルスに関連する問題に影響を与えるかどうかは不明である。 女性と子どもの健康は、避妊から大きな恩恵を受ける。このような利点があるにもかかわらず、また妊娠を避けたいにもかかわらず避妊をしない女性が世界的にかなり多い。 近年の携帯電話の急速な普及により、必要な時にいつでも、どこでも、サービスへのアクセスが制限された人々へも届く、携帯電話を介したヘルスケアの提供への関心が高まっている。 エビデンスの特定および評価を行った方法は? 携帯電話で配信される介入の使用と避妊の使用への影響を評価した研究について、医学データベースを検索した。その結果、高所得国(11試験)と低所得国(12試験)の両方において、11カ国で実施された12,79...

高血圧に対する第一選択薬として利尿薬を投与する場合、他の種類の薬剤と比較して、どのような利益と不利益があるのか

1 year 10 months ago
高血圧に対する第一選択薬として利尿薬を投与する場合、他の種類の薬剤と比較して、どのような利益と不利益があるのか 要点 - 高血圧治療の第一選択薬として、サイアザイド系やサイアザイド系類似の利尿薬を使用した場合、β遮断薬、カルシウム拮抗薬、ACE阻害薬およびα遮断薬を第一選択薬として使用した場合と比較して、心血管系の有害事象(心血管イベント)が減少する可能性が高い。 - 総死亡率は、利尿薬と他の種類の薬剤との間に差がない可能性が高い。 - 利尿薬を第一選択薬として使用した場合、カルシウム拮抗薬やα遮断薬を第一選択薬として使用した場合と比較して、全心血管イベントや心不全が減少する確率が高い。 - 利尿薬を第一選択薬として使用した場合、β遮断薬、カルシウム拮抗薬、ACE阻害薬およびα遮断薬を第一選択薬として使用した場合と比較して、望ましくない影響や悪影響(有害事象)による研究からの脱落者が減少する可能性が高い。 高血圧(症)とは何か 高血圧(症)とは、安静時血圧により、軽度(140~159/90~99mmHg)、中等度(160~179/100~109mmHg)、重度(180/110mmHg以上)と定義される。高血圧がうまくコントロールされていないと、脳卒中、心筋梗塞、心不全、腎障害などにつながることがある。60歳以上の高齢者にみられる中等度から重度の高血圧に対する降圧薬の使用は、このよ...

Introducing the new Cochrane Handbook for Diagnostic Test Accuracy

1 year 10 months ago

Cochrane is delighted to unveil the fully comprehensive edition of the Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. Designed for authors, editors, and researchers involved in Cochrane Reviews and systematic evaluations of test accuracy, this invaluable resource provides an extensive guide encompassing the most advanced methodologies and best practices. Whether you're a novice researcher or a seasoned expert, this groundbreaking Handbook equips you with the latest methodologies and expert tips, serving as an invaluable resource for conducting diagnostic test systematic reviews. This Handbook paves the way for better-informed healthcare choices, propelling us towards a future where the impact of medical tests is fully optimized.



This is Cochrane's second Handbook, following the success of the acclaimed Cochrane Handbook for Systematic Reviews of Interventions. Cochrane’s Editor in Chief, Karla Soares-Weiser warmly welcomed today’s launch, "This Handbook is an excellent addition to the Cochrane Handbook collection and represents a hugely collaborative effort from numerous methodologists, authors, and editors across Cochrane. Cochrane systematic reviewers and the evidence-based community now have access to well-respected guidance that will strengthen the skills, knowledge and standards of systematic reviewers of test accuracy across the world."

Under the guidance of the experts in the Cochrane Screening and Diagnostic Tests Methods Group, this Handbook is thoughtfully divided into three comprehensive parts. The first section provides insights into the intricacies of Cochrane Reviews, specifically focusing on diagnostic test accuracy. In the second section, readers are introduced to test accuracy studies, exploring the circumstances in which it may be appropriate to conduct them. The third and final section delves into the methodologies employed in systematic reviews of test accuracy, offering expert guidance on data collection, risk of bias assessment for included studies, and conducting impactful meta-analyses. This holistic approach ensures that readers are equipped with the necessary tools to conduct the systematic review and then confidently present their findings.

The first edition Handbook includes:

  • An introduction to planning a Cochrane Review of diagnostic test accuracy, along with a supplementary protocol template that can be used by Cochrane or non-Cochrane authors.
  • Core guidance on understanding the primary research included in systematic reviews of test accuracy to enable authors to make informed decisions in their review’s design, including the evaluation of medical tests, the design of test accuracy studies and understanding test accuracy measures.
  • New guidance on defining the review question, covering how the review’s objective relates to the population, index tests and target condition and review’s eligibility criteria.
  • Substantial developments on searching for and selecting studies, extracting data and assessing the risk of bias and applicability in included studies, which takes readers step-by-step through what they need to consider and at what point during the review.
  • Brand new guidance on undertaking meta-analysis complements the updated understanding meta-analysis chapter, and includes supplementary code and datasets that you’ll need to complete the analyses in different software.
  • Updated guidance on presenting findings and drawing conclusions.
  • New guidance on writing a plain language summary, including a template that can be used by Cochrane or non-Cochrane authors.

The Handbook has been written by a team of authors and editors, led by Senior Editors Professor Jon Deeks and Professor Patrick M Bossuyt, alongside Associate Editors Mariska Leeflang and Yemisi Takwoingi. Professor Patrick  Bossuyt, Senior Editor of the Handbook, also said, “The new Handbook reflects current best practice based on the latest methods research, and provides the only such comprehensive guide to conducting systematic reviews of test accuracy. We are immensely proud of the collective contributions from the authors, peer reviewers and methodologists who have informed its gestation over the years; we would like to thank them all as we would not have been able to create this Handbook without them.”

Professor Jon Deeks, Senior Editor of the Handbook, said, “Cochrane Reviews of diagnostic test accuracy have a huge impact globally. Cochrane Reviews underpin many clinical guidelines, including World Health Organization ones. Cochrane evidence also informs the WHO Essential Diagnostics List, which covers many areas of infectious disease and addresses the need for countries to make essential diagnostics more accessible and affordable. This new guidance for both new and experienced authors will strengthen our ability to develop highly impactful reviews that make a real difference in people’s lives.”

Don't miss out on this game-changing resource! The online version of the Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy is available for free, offering immediate access to its wealth of knowledge as a PDF. But for those seeking convenience and a cherished addition to their collection, the physical edition of the Handbook and the E-book is also available.

 

Thursday, July 20, 2023 Category: The difference we make
Muriah Umoquit

Breaking language barriers: Cochrane adds Bahasa Indonesia to translation efforts

1 year 10 months ago

With over 198 million speakers globally, Bahasa Indonesia is the official language of Indonesia, the world's fourth most populous country. Recently Bahasa Indonesia has been added along with four other new languages to Cochrane.org and the Cochrane Library. Adding Bahasa Indonesia to the list of 21 languages that plain language summaries are translated in, marks a significant stride in addressing the healthcare information needs of this extensive and diverse population. This inclusion not only breaks linguistic barriers but also empowers individuals to make evidence-informed health decisions globally.

From left to right: Datu Respatika, Lukman Ade Chandra, Kristia Hermawan, Anggraeni Ayu Rengganis (Translation Manager), Afrilia Intan Pratiwi, Alfia Fatma Zaharo, Mawaddah Ar Rochmah, Detty Siti Nurdiati (Director of Cochrane Indonesia), Ajeng Viska Icanervilia.

The addition of the new language addition is due to the strong collaboration between Cochrane Malaysia and Cochrane Indonesia. They have shared a longstanding history of mutual support since their inception and this new Indonesian translation project has deepened that bond between the teams. Cochrane Malaysia has graciously extended their assistance and expertise to support Cochrane Indonesia in establishing their translation project.

“I am particularly happy about it because I feel a part of the project. Malaysia and Indonesia are like siblings, and we try to support each other where we can."

- Prof. Jacqueline Ho, Cochrane Malaysia Co-Director

 

At the outset, Teguh Haryo Sasongko, Cochrane's Malaysia Translation Project Manager, arranged an online meeting with Cochrane Indonesia to outline the management of the Malaysian project and discuss how the team encourages its volunteers. In May of this year, during the Indonesian team's visit to Malaysia, they connected with Nila Pillai (as shown in the above photo; seen in the bottom right sharing with the Indonesian team). Nila has been serving as the Cochrane Malaysia Support Officer and coordinator of Cochrane Malaysia's Malay Translation Project since its inception in 2015. Nila shared insights on how she manages the translation project, highlighting both challenges and successes. The two teams recently collaborated in organizing joint Cochrane training workshops in both countries, with plans for further collaboration in various domains.

“Indonesia has the 4th largest population in the world and even though Malay and Indonesian have some similarities, being able to offer Cochrane evidence in Bahasa Indonesia, Indonesia’s main and official language, marks an important milestone for us."

- Dr. Detty Nurdiati, Cochrane Indonesia Director

Thursday, August 17, 2023
Muriah Umoquit

Cochrane seeks Assistant Editor - remote

1 year 10 months ago

Specifications: Permanent – Full Time
Salary:  £ 30,000 per Annum  
Location: Remote - Ideally based in the UK, Germany or Denmark. Candidates from the rest of the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Closing date: 29 July 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.
Cochrane's Evidence Production & Methods Directorate (EPMD) ensures that the Cochrane Library maintains its reputation as the international source of trustworthy, independent, and relevant information to guide healthcare decisions. The EPMD houses the Central Editorial Service, the Central Production Service and also supports review development to ensure that the Cochrane Library continues to produce high quality evidence syntheses that meet the needs of users.   
    
Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect:  

  • An opportunity to truly impact health globally  
  • A flexible work environment  
  • A comprehensive onboarding experiences
  • An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  • For further information on the role and how to apply, please click here.
  • The deadline to receive your application is 29th July, 2023.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
  • Read our Recruitment Privacy Statement
Tuesday, July 11, 2023 Category: Jobs
Lydia Parsonson

エストロゲン療法は閉経後女性の骨盤臓器脱の治療に役立つか?

1 year 10 months ago
エストロゲン療法は閉経後女性の骨盤臓器脱の治療に役立つか? 要点 - 14件の研究がこのレビューの選択基準を満たしたが、最も関心のある比較を扱った研究はなかったため、閉経後女性の骨盤臓器脱に対するエストロゲン療法の効果については不明である。 - 閉経後女性の骨盤臓器脱に対する、エストロゲン療法単独または他の治療法との併用による効果について評価するためには、さらなる研究が必要である。 骨盤臓器脱とは? 骨盤臓器脱とは、女性の子宮、膀胱、直腸が正常な位置から腟の中に下がってしまうことである。この病気はよく見られるもので、少なくとも一度出産経験のある50歳以上の女性の50%が罹患している。子宮摘出術を受けた女性の6%~12%が骨盤臓器脱を経験する。年齢が高く、出産回数が多く、太っている女性は骨盤臓器脱になりやすい。骨盤臓器脱の女性は、腟に「何かが下りてくる」感覚や、性行為時の不快感や排尿障害など、QOL(生活の質)や身体イメージに悪影響を及ぼすその他の症状を有することがある。 知りたかったこと 骨盤臓器脱の治療には、多くの臨床医がエストロゲン療法(ホルモン療法の一種)を処方しており、ペッサリー(腟内に挿入して支える器具)や手術などの他の治療法と併用することもある。しかし、このアプローチの利益は不明である。エストロゲン療法を単独で、あるいは他の治療法と併用することで、閉経後の女性の骨盤臓...

お腹の中の赤ちゃんの発育が遅い妊婦の胎盤機能を改善する薬

1 year 10 months ago
お腹の中の赤ちゃんの発育が遅い妊婦の胎盤機能を改善する薬 レビューの論点 妊娠の約0.4%で、胎児が発育不良になる。それは、胎盤が十分な栄養を供給できないからである。これらの赤ちゃんは、栄養と酸素の供給が不十分なため、子宮内で死亡する危険性が高い。そのため医師は、子宮の外で栄養や酸素を与えるために、赤ちゃんが満期になる前に出産させることが多い。しかし、このような早産は、赤ちゃんが未熟児で出生体重が非常に低いことを意味する。その結果、生後数ヶ月からその後長期にわたって、深刻な健康問題を抱える危険性がある。このコクラン・レビューの目的は、一酸化窒素経路に作用する薬剤(シルデナフィル、タダラフィル、L-アルギニン、ニトログリセリンなど)が、これらの赤ちゃんの転帰を改善するかどうかを調べることである。発育遅延が胎盤の問題に起因する赤ちゃんだけを調査した。この疑問を検証するために、関連するあらゆる研究を集めて解析した。 重要である理由 現在のところ、胎盤機能を改善する有効な治療法は知られていないため、早産させることが唯一の選択肢となっている。そこで、母体から胎盤への血流を改善する薬に関心が集まっている。これらの治療の目的は、胎盤の働きを良くして出産前の赤ちゃんの成長を改善することである。その結果、出産の時期を遅らせることができれば、最終的に健康な状態で生存する可能性が高くなるからである。 ...

From complexity to clarity: Cochrane unveils #BetterPresentations templates for accessible and engaging talks at the Cochrane London Colloquium

1 year 10 months ago

The Cochrane Colloquium is a premier event for those interested in evidence-based healthcare decision-making. It brings together individuals involved in evidence production, dissemination, implementation, and policy-making, as well as those making individual healthcare decisions. The 2023 Cochrane Colloquium will take place in London, UK from 4th to 6th of September 2023, with satellite events on 3rd of September. Registration is still open!

Presentations form a cornerstone of the Cochrane London Colloquium, providing a platform for in-depth exploration of topics and fostering future collaborations. With approximately 46 long oral presentations and 180 short oral presentations scheduled this year, the importance of accessibility in these sessions cannot be overstated. By embracing accessible presentations, the colloquium aims to enhance knowledge transfer, particularly for individuals whose native language is not English or who may face challenges related to disabilities or neurodivergence.

To address this challenge, we have collaborated with a team of researchers who are investigating the accessibility of presentations at academic conferences. As part of their work, they have created Cochrane Colloquium poster templates based on the latest evidence. In their ongoing efforts to drive innovation, the team has now developed Cochrane Colloquium PowerPoint presentation templates. Eager to delve into their evidence-based work, we sat down with the team to gain deeper insights into their latest contributions.

Can you tell us a bit about your elite research team so we have an understanding of how you are approaching academic posters and presentations?
Sure! We’ve built a diverse team of people from across IPG Health (Emily Messina, James Wells, Noofa Hannan, and Anja Petersen), and our team includes Zen Faulkes, author of the book “Better Posters” and founder of the Better Posters blog, Mike Morrison, the psychologist who created a redesign for scientific posters that went viral and started the #BetterPoster movement. We’ve all been to conferences where and crowded poster halls with posters just packed with information and gotten lost in talks with either too few slides or way too many slides. So we wanted to gather some data, specifically from those with accessibility needs or disabilities, on how we can make conference presentations a better, more accessible experience, for everyone.   

Similar to academic posters, the presentation’s role is to communicate the top research insights very quickly and engagingly. What do you see as the unique challenges that presentations give over posters?
Presentations are given more physical time to play out in front of a captive audience; you have the opportunity to fit in more information and provide both audio and visual communication. But it is still important to keep to your key message. There is a tendency sometimes to want to cram as much information into a talk as possible. However, this leads to a talk where the audience is overloaded and doesn’t remember half of what was presented. So in oral presentations, its also important to keep to your core message and keep in mind how much time you have.

Additionally, the extended platform of oral presentations also presents challenges —balancing the inclusion of ample information while ensuring accessibility for individuals with low vision, processing disorders, or other environmental conditions of the room such as dim lighting or sound distortion. You also need to ensure that anyone who may be hard of hearing or D/deaf, or perhaps neurodivergent, or folks who may struggle with the speakers accent or language can still follow along. A clear, concise, and decluttered presentation can help navigate through these challenges! 

Could you elaborate on the recommendations included about reducing clutter in presentations?
Sure! Our data show that conference attendees really want large, readable figures along with clear and concise text. Research indicates this greatly improves information retention. It's crucial to include only the necessary content to tell your story, as clutter can distract and confuse the audience. We encourage presenters to triage any additional content and ask themselves, "Does this enhance the clarity of my message?" If not, it's best to leave it out.

The idea is to have just enough information on the slide to reinforce your message and so that if the audience misses something you said, they can still follow along. Everything else should be left off the slide.

How important is plain language in creating accessible presentations?
The significance of plain language cannot be overstated! The Cochrane Community has already recognized its importance through the inclusion of plain language summaries with each Cochrane Review. However, the need for plain language extends to presentations as well. By employing clear, concise, and jargon-free language, researchers can successfully convey their findings to a wider audience. Prioritizing clarity and avoiding unnecessary complexity is crucial in ensuring effective communication. This holds particular relevance at Cochrane London, where the audience comprises individuals ranging from patients to advanced researchers.

Cochrane is adopting the #BetterPreseration design as the official presentation template for the Cochrane Colloquium. What can presenters expect?
Our aim is to empower researchers to effectively communicate their work to a diverse audience while ensuring accessibility and clarity. By adopting the #BetterPresentations templates, researchers can elevate the impact of their findings, facilitate knowledge transfer, and foster inclusivity within academic conferences. The #BetterPresentations templates are fully editable, allowing researchers to include their institution's logo and adapt the templates to suit the requirements of various academic conferences. This flexibility ensures that the templates can be used for the Cochrane London Colloquium or any other academic event.

And please get creative in how you make your presentations ‘feel’! Communicating study-relevant emotion is part of good science communication. We're excited to see what you come up with; please tag your social media posts about your presentations with #BetterPreserntations so we can see them!

And what can attendees of the Colloquium expect?
With the implementation of more engaging presentations, the Cochrane London Colloquium aims to delve into the fascinating and captivating aspects of research, enabling attendees to swiftly identify the presentations that align with their interests. This will pave the way for meaningful follow-up discussions with presenters, providing a valuable opportunity to delve deeper into the subject matter. We are looking forward to getting attendees' feedback, which will be collected through the official post-Colloquium survey. Your insights will play a crucial role in shaping future iterations of templates and ensuring an even more enriching experience for all.

Friday, July 7, 2023
Muriah Umoquit

Cochrane expands global reach: Pilot project introduces new language translations

1 year 10 months ago

Cochrane evidence is now accessible in 21 languages, breaking linguistic barriers and empowering global evidence-informed health decisions.

Many people do not have access to high-quality health information, because it is not available in a language they understand. Only about 6% of the world’s population are native English speakers and 75% don’t speak English. 

The focus of our translation activities at Cochrane is on plain language summaries. Plain language summaries are created using standard content and structure and are written in accessible language. Looking to expand past the 16 languages we currently offer these summaries in, we have added five additional languages as part of a 2023 pilot project. The following groups will now be translating them into these languages: 

Although the pilot project is currently unfunded, the participating teams receive access to Cochrane's technical translation infrastructure, training, and support. Their responsibilities include translating a limited number of plain language summaries per month and conducting knowledge translation activities in their respective languages. The success of the pilot project may lead to future expansions.

"I am thrilled by the expansion of Cochrane's language offerings and the remarkable dedication of our volunteers. Their contributions have made Cochrane evidence available in 21 languages, enabling us to reach a wider audience and facilitate evidence-informed health decisions across the globe. I extend my deepest gratitude to all the volunteers who have played a pivotal role in this exciting endeavor."

- Judith Deppe, Cochrane Multi-language Programme Manager

 

Tuesday, July 18, 2023 Category: The difference we make
Muriah Umoquit

軽度から中等度の認知症患者に対する認知リハビリテーションの利点とリスクは何か?

1 year 11 months ago
軽度から中等度の認知症患者に対する認知リハビリテーションの利点とリスクは何か? 要点 認知リハビリテーションは、認知症患者自身が重要な日常生活の管理を行うのに役立つ。 全体的な機能や幸福度の向上に有効な認知リハビリテーションの方法を探ることが今後の課題である。 認知症とは何か? 認知症とは、脳の変化によって引き起こされ、時間の経過とともに悪化する一連の症状である。ある種の認知症では、記憶、計画、集中、およびコミュニケーションを行うことが困難となる。これらの、および他の思考障害は、「認知障害」という用語で総称される。認知障害により、日常生活や、できるだけ長く自立した生活を送ることが困難になる。 認知リハビリテーションとは何か? 認知リハビリテーションとは、認知症患者に対して個別に設計された介入である。通常、患者の自宅において1対1のリハビリテーションが行なわれる。患者は、よりよく管理したい、またはより自立して行いたいと思う日常的な活動や作業を決定する。医療従事者は、患者にとって重要なそれらを改善できるようなリハビリテーション計画を提案し、患者と実施する。このプロセスには患者の家族も参加して行われることが多い。 何を調べようとしたのか? 患者にとって重要な作業や活動を行うこと、日常生活の管理を行うこと、物ごとの管理に自信を持つこと、抑うつや不安が改善すること、および幸福感を持つことに...

Cochrane Lifetime and Emeritus Members List

1 year 11 months ago

Cochrane is proud to announce new lifetime and emeritus memberships, recognizing the extraordinary contributions of individuals who have made an exceptional, long-standing contribution to Cochrane’s work and leadership. 

Cochrane's strength is in its collaborative, global community. Over the last 30 years, our members and supporters from more than 130 countries have worked together to produce credible, accessible health information and help inform health decision-making. Though we are spread out across the globe, our shared passion for health evidence unites us. 

Cochrane’s Membership scheme helps reward everyone who helps provide produce and disseminate Cochrane evidence, as well as provide leadership for our strategic goals. Membership is a valuable addition to résumés, gives you voting rights, and opens opportunities for getting involved in governance and learning opportunities. 

We are proud to recognise extraordinary contributions to Cochrane with Emeritus and Lifetime Memberships. These are awarded to those who have contributed to Cochrane’s success over many years and are now reducing or ending their active time with Cochrane.

Emeritus members: 
Individuals who made a significant long-standing contribution to the leadership of the organization.

  • Gerd Antes
  • Sally Bell-Syer
  • Xavier Bonfill
  • Iain Chalmers
  • Kay Dickersin
  • Muir Gray
  • Jini Hetherington
  • Sophie Hill
  • Anne Lydiatt
  • Nandi Siegfried
  • Prathap Tharyan
  • Hywel Williams

Lifetime members:
Individuals at all levels of the organization who have made an exceptional, long-standing commitment to Cochrane's work.

  • Peter Herbison
  • Anne Lethaby

Congratulations to all the inductees and a warm thank you for your contributions! 

Wednesday, July 5, 2023
Muriah Umoquit

社会的支援介入は心臓病患者の助けになるか? 

1 year 11 months ago
社会的支援介入は心臓病患者の助けになるか? 要点 社会的支援や社会的ネットワークプログラムが心臓病患者の助けになるという明確なエビデンスはない。 これらのプログラムによって、生活の質(QOL)や血圧がある程度改善する可能性がある。 このレビューによれば、社会的支援や社会的ネットワークへの介入は心臓病患者を助ける可能性があるが、有効性を証明するためには、より質の高い、明確に報告された試験であることを示唆している 心臓病とは何か? 「心臓病」とは、冠動脈疾患(心臓の血管の病気)、不整脈(心房細動などの不整脈)、心臓感染症、先天性心疾患など、心臓に影響を及ぼすさまざまな疾患を指す。心臓病の一般的な症状は、胸痛(狭心症)と心臓発作(心筋梗塞)である。心臓病は世界中で早期死亡の原因となっている。現代の心臓リハビリテーションプログラムは、一般的に身体的、精神的、社会的要因に対処し、心臓病患者の日常生活を支援するようにデザインされている。 なぜ社会的支援プログラムが心臓病患者の助けになるのか? 低レベルの社会的支援や社会的孤立が、心臓病患者の健康状態の悪化につながることを示唆するいくつかのエビデンスがある。社会的ネットワークまたは社会的支援介入は、健康的な行動を支援するために社会的関係を意図的に利用し、パートナー、家族、友人、他の仲間、または介護者が関与することがある。このようなプログラムが心...

Cochrane seeks Research Integrity Editor - Remote, flexible

1 year 11 months ago

Specifications: Permanent
Salary:  £40,000 per Annum  
Location: Flexible. Cochrane's Central Executive Team is able to offer employment contracts in the UK, Germany or Denmark, and consultancy contracts outside these countries
Closing date: 11 July 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

Cochrane is committed to independence, transparency, and integrity in healthcare research. The role of the Research Integrity Editor is to support and strengthen this commitment through policy development, implementation, research, advocacy, and community outreach.   

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect: 

  • An opportunity to truly impact health globally
  • A flexible work environment
  • A comprehensive onboarding experiences
  • An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values. 

How to apply

    Tuesday, June 27, 2023 Category: Jobs
Harry Dayantis

Cochrane seeks Executive Editor - Remote, flexible

1 year 11 months ago

Specifications: Permanent – Full Time
Salary:  £55,000 per Annum  
Location: Remote - Ideally based in the UK, Germany or Denmark. Candidates from the rest of the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Closing date: 11 July 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Executive Editor will be expected to prioritise and delegate editorial tasks as appropriate. The role holder will need to be an advocate for the Editorial Service internally and externally to Cochrane and remain alert to immediate demands of delivering high-quality review content for publication in a timely fashion.        

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

  • An opportunity to truly impact health globally  
  • A flexible work environment  
  • A comprehensive onboarding experiences
  • An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  Tuesday, June 27, 2023 Category: Jobs
Harry Dayantis

Explore the Anne Anderson Walk at the Cochrane Colloquium - A Self-Guided Experience

1 year 11 months ago

Cochrane UK is hosting Cochrane’s Colloquium an eagerly anticipated event taking place in the vibrant city of London, UK from 4-6 September 2023. Under the theme "Forward together for trusted evidence," the 2023 Cochrane Colloquium promises to be a groundbreaking experience, featuring a dynamic blend of learning opportunities, networking sessions, inspiring plenary speakers, and engaging events.

Among the exciting highlights of the Colloquium, we are thrilled to unveil the captivating route for 2023 Anne Anderson Walk, an accessible self-guided journey that guides participants through the rich health history surrounding the conference centre and notable landmarks of London. With three eventful days of Colloquium content, we encourage you to indulge in this self-guided tour, granting yourself the opportunity to relax and proceed at your own tempo. Whether you choose to meet colleagues before, during, or after the Colloquium or simply take an evening stroll, this experience is designed to accommodate your personal preferences.

In an exclusive interview, we had the pleasure of speaking with Anna Doherty, the person behind the map artwork of the Anne Anderson Walk. Anna shared her inspiration for the art and provided insights into what participants can expect along the route.

Hi Anna! Our Cochrane Community always finds it interesting to learn the backstory of things and learn more about people. Could you tell us a bit more about yourself?
“Hi! I’m an illustrator and author from Edinburgh, Scotland and now based in Cambridge, UK. Ever since I was very small, I’ve always enjoyed drawing, so when I finished school I went to study illustration at Duncan of Jordanstone College of Art and Design. After graduating, I wasn’t quite done with education! My favourite part of my undergrad had been narrative-based illustration, so I decided to study a masters in Children’s Book Illustration at Cambridge School of Art. Since graduating there, I’ve been working on a mixture of illustrating picture books, science illustration, and other little projects. I now have fourteen illustrated picture books published, some of which I wrote too! I am especially excited about working in non-fiction, which is why I think I enjoy science illustration so much because I love learning new facts and finding fun new things to share with people. The idea that something I have illustrated might teach someone something new excites me! I have a mini-series called Fantastically Feminist which focuses on celebrating stories of amazing women. I wanted to make space for kids to read in, that not only showed that everyone should be equal and that anyone can do anything regardless of their gender but also celebrated women who struggled to try and make things more equal for the rest of us in brilliant ways.”



You've illustrated the 2023 map of the Anne Anderson walk. But you're not new to Anne Anderson! - You've worked on Anne Anderson artwork that is included in Lifeology's Historic STEAM Heros card deck. Anne Anderson is a beloved person in the Cochrane Community. Can you tell us a bit about working on that artwork? 
 “Absolutely! It was a joy to learn more about this remarkable Scottish scientist and weave her story into the STEAM hero illustration. I thoroughly enjoyed delving into Anne Anderson's life, work and contributions, and understanding her role in the stream of thinking that gave birth to evidence-based healthcare - and ultimately led to the development of Cochrane. I was honoured to be a part of introducing Anne to a wider audience and celebrating her as a STEAM Hero.”

The Anne Anderson Walk is a cherished annual social event for Cochrane, where attendees explore the Colloquium host city and make a donation to next year’s Anne Anderson Award. Normally this walk is done as a group with a tour guide but this year to increase accessibility we are using a map to let people go at their own pace. What do you think of the route?
"After the organisers had mapped out the route, tested it several times, and then passed it on to me to illustrate, I was truly amazed at how many fascinating health history locations were close to the conference centre! Living in Cambridge, I’m so close to London myself, and yet I had no idea there were so many health history spots to visit all in a relatively small area! Attendees of the conference are in for a real treat as they self-guide and explore so much history right on their doorstep. There are iconic landmarks like Big Ben and the Florence Nightingale Museum along the route, however what excited me the most were the hidden gems that might be easily overlooked without the guidance of the route directions and details. Some I had never heard of before – so I was extra excited to be able to share them with more people through this map! I was captivated by the fascinating women and hidden tales of health history that unveil themselves along the Anne Anderson Walk, making it exciting even for those who may have already explored London before. Plus, the map is easy to navigate for people new to the city!"

What was your favourite aspect of the map to draw?
"That's a tough question! There were so many captivating elements to bring to life on the map. While I enjoyed drawing iconic London landmarks like Westminster Abbey and Big Ben, if I had to choose, my favourite feature would be the Mary Seacole Statue. The statue itself is an amazing piece of art, but what makes it even more significant is that many people might unknowingly pass by it without venturing into the garden to explore further. I will always have a special space in my heart for any Woman in STEAM, but Mary Seacole in particular has been a fascinating historical figure to me for a while – and yet I had no idea she had a statue! I hope this map can be a step in bringing a wider audience to her. A Scottish-Jamaican nurse, Mary overcame racism and injustice to provide care for soldiers during the Crimean War. Her story is a one of resilience and the power of nursing in the face of adversity. We didn’t have space to include an icon from every location you can visit on the map, so including the Mary Seacole Statue was a deliberate choice to shed light on her remarkable contributions. And I think that Anne Anderson would approve of this addition, as it reflects her passion for highlighting unsung heroes in the field of healthcare!”



Your style is super cute - such a charming aesthetic! How do you do your artwork?
“Thank you so much! I would describe my art style as digital mixed media. My creative process typically involves drawing on a Wacom tablet, which is connected to my computer. As I draw on the tablet, the marks I make appear on my screen in Photoshop. I use a variety of brushes and layered textures to achieve different effects. To add more depth and visual interest, I incorporate scanned textures that I've created using things like ink and paint. This blending of digital and traditional elements allows me to bring a unique aesthetic to my artwork.”

Well, Anna, your map artwork has truly captured our hearts. Thank you so much for taking the time to speak with us and share your insights. We are confident that everyone will love the map and route you've created!

Don't miss the opportunity to explore the captivating Anne Anderson Walk during the Cochrane Colloquium. Get ready to embark on a remarkable journey through London's health history and significant landmarks - all steps away from #CochraneLondon!  

Thursday, June 29, 2023
Muriah Umoquit

月経前症候群治療用ドロスピレノン配合避妊薬

1 year 11 months ago
月経前症候群治療用ドロスピレノン配合避妊薬 レビューの論点 ドロスピレノンとエストロゲンを含有する避妊薬が、プラセボ(ダミー)ピルまたは他の避妊薬と比較して、PMSの女性の月経前症候群(PMS)症状の改善に有効であるかどうかを調べようとした。また、女性が経験するかもしれない副作用についても調べたいと思った。 背景 PMSはよくある問題だ。重症のものは月経前不快気分障害(PMDD)と呼ばれる。症状には、行動の変化や日常生活に影響を及ぼす身体的徴候や症状が含まれる。これらの症状を治療するために、黄体ホルモンとエストロゲンホルモンを配合した避妊薬が研究されている。米国では、ドロスピレノンに低用量エストロゲンを配合した避妊薬がPMDDの治療薬として承認された。 研究の特性 858人の女性を対象とした5件の試験が見つかった。すべての試験で、ダミーピルとドロスピレノンと低エストロゲンピルが比較された。女性の大半は、試験前にPMSの重症型であるPMDDを患っていた。エビデンスは、2022年6月現在のものである。 主要な結果 3か月後、ドロスピレノンと低エストロゲンピルを服用した女性は、ダミーピルを服用したグループよりも月経前症状の重症度が低かった。ドロスピレノンと低エストロゲンピルを服用している女性は、より多くのことができ、より多くの社会的活動や友人がいると答えた。しかし、ドロスピレノンと低エ...