重度で持続する神経性食欲不振症患者に対する心理療法 要点 1．重度かつ持続する神経性食欲不振症患者を対象とした1件の小規模研究では、認知行動療法と専門家による支持的臨床管理という2種類の療法が比較された。 2．特定の治療法が他の治療法よりも効果的かどうかを確実に言えるだけのエビデンスはない。 3．重度かつ持続する神経性食欲不振症患者に対する治療の効果を調査するため、より大規模な研究が必要である。 なぜこのレビューが重要なのか？ 神経性食欲不振症は摂食障害であり、深刻な精神疾患である。神経性食欲不振症の人は通常、体重が非常に少なく、体重が増えることを強く恐れ、自分の体重に対する歪んだ認識を持っている。神経性食欲不振症の主な治療法は、特定の心理療法と集学的な身体的・栄養的ケアを組み合わせることである。利用できる主な療法は、認知行動療法（CBT）、専門家による支持的臨床管理（SSCM）、神経性食欲不振症の成人のためのモーズレイ式治療（MANTRA）、焦点化精神力動的精神療法（FPT）である。いずれも栄養や身体的なケアに関するアドバイスやカウンセリングを提供するが、心理的な部分のどこに重点を置いているかという点が異なる。CBTは、神経性食欲不振症の行動の根底にある考え（認知）、例えば太ることへの恐怖に対処し、積極的な行動戦略（例えば、不安を引き起こす食物を少しずつ量を増やしながら食べてい...

Tuesday, August 22, 2023

保育園、幼稚園、児童養護施設における健康的な食事プログラムは、どの程度成功しているのだろうか？ 要点 - 幼児教育と保育（ECEC）の場（保育園、幼稚園、家庭的保育など）で実施される健康的な食事プログラムは、子どもの食事の質を改善し、果物の消費量を増加させ、野菜の消費量に好ましい影響を与える可能性があり、あまり健康的でない食品や砂糖入り飲料の消費量には影響を与えない可能性がある。子どもの体重に良い影響を与え、過体重や肥満のリスクを減らす可能性がある。 - 健康的な食事介入が節約になるのか、望ましくない効果をもたらすのかは、これらの点について情報を提供した研究がほとんどないため、わからない。 - 低中所得国のエビデンスはほとんど見つからなかったが、高所得国の健康的な食事プログラムは子どもの健康に役立つ可能性がある。これらのプログラムを実践するために、教育者やスタッフをどのようにサポートすればいいのかわからない。低所得国でのプログラムの提供やその効果について、もっと研究が必要である。 なぜ小児の食生活を改善することが重要なのか？ 不健康な食事は、心臓病、2型糖尿病、ある種の癌を含む多くの長期的な病気のリスクになる。調査によると、不健康な食生活が原因で死亡する人は世界で1,100万人を超えると推定されている。食生活の行動や嗜好は、人生の早い時期に確立され、成人期まで続く。 健康的な食事...

小児の逆流性食道炎に対する薬 レビューの論点 胃食道逆流の赤ちゃんや子どもにとって、最も安全で最善の治療法は何か？ 要点 - 胃食道逆流症/逆流性食道炎の乳児に対する薬物療法のエビデンスは非常に不確かである； - 胃食道逆流症の小児に対するプロトンポンプ阻害薬の効果については、エビデンスが非常に不確かである。他の薬に関しては、結論を出すのに十分な証拠はなかった。 胃食道逆流とは何か？ 胃食道逆流は、胃の内容物が食道に逆流することで起こる。ほとんどの赤ちゃん（1歳未満）は逆流の症状が治まるが、薬は役に立つのだろうか？子供（1歳以上）も大人と同じように逆流することがある。逆流は正常な場合もあるが（「生理的逆流」）、乳幼児や小児の場合、食道が炎症を起こし（食道炎）、痛みや体重減少などの症状を引き起こすことがある。逆流の厄介な症状は「胃食道逆流症」（GORD）と呼ばれる。 胃食道逆流はどのように治療するのか？ 胃の内容物を濃くする薬（アルギン酸塩）、胃酸を中和する薬（ラニチジン、オメプラゾール、ランソプラゾール）、胃を早く空にする薬（ドンペリドン、エリスロマイシン）などがある。 何を調べようとしたのか？ 私たちは、赤ちゃんや子供の逆流を抑える最善の方法を知りたかった。私たちは、薬が乳幼児や小児の気分（症状スコア）を良くするか、食道を治すか（これは内視鏡検査（小さなカメラを食道に入れて検査...

メンタルヘルスとウェルビーイング（幸福）を向上させるツールとしてのメンタルヘルス・ファーストエイド このレビューの重要性は？ メンタルヘルス・ファーストエイドとは、「精神衛生上の問題を発症している人、精神衛生上の問題が悪化している人、精神衛生上の危機に陥っている人に提供される援助」と定義されている。ファーストエイドは、適切な専門家の援助を受けるか、危機が解決するまで行われる。 メンタルヘルス・ファーストエイド（MHFA）は、一般の人々にメンタルヘルス・ファーストエイドを教えることを目的としたトレーニングプログラムである。MHFA訓練はカスケード・モデルで行われ、認定された指導員が研修を実施し、受講生がメンタルヘルス・ファーストエイドのスキルを習得できるよう指導する。訓練を受けた受講生は、職場や組織、地域社会の人々にメンタルヘルス・ファーストエイドを提供する。MHFA研修は、精神衛生問題についての知識を深め、それによって精神衛生問題につきまとうスティグマを軽減することを目的としている。受講生は、支援を受ける人への迅速な支援の提供方法と、必要なサービスに繋げる方法を学ぶ。 このレビューに関心を持つ人は誰か？ MHFAトレーニングを検討している個人 従業員と雇用主 政策決定者 このレビューで明らかにしたいことは？ メンタルヘルス・ファースト・エイド（MHFA）研修が、MHFA研修が実施...

Monday, August 21, 2023

Cochrane appoints new Governing Board interim Chair, Jordi Pardo Pardo and says farewell to two outgoing Trustees, Catherine Marshall and Tracey Howe

Cochrane is an international non-profit network, which sets the gold standard for synthesizing health research findings  to facilitate evidence-based health care.  Cochrane Reviews, found in the Cochrane Library, are up-to-date, follow a rigorous scientific methodology, and are free from commercial conflicts of interest. Health professionals, patients, and policy makers trust Cochrane Reviews for their healthcare decision-making. Cochrane works with researchers, health professionals, patients, policy makers, and media representatives from around the world to make Cochrane Reviews relevant and usable.

Cochrane's Governing Board is responsible for setting Cochrane's strategic direction and overseeing the work of the Chief Executive Officer, Editor in Chief, and Central Executive Team.

Cochrane’s Governing Board has appointed Jordi Pardo Pardo as new interim Chair. He will be taking over from Catherine Marshall and Tracey Howe who have been serving as Co-Chairs of the Board. Catherine's maximum four-year term will conclude in September 2023, and Tracey, whose term was set to end September 2024, has decided to step down this September due to personal circumstances.

Jordi Pardo Pardo, a longstanding member of the Board, former Managing Editor of Cochrane Musculoskeletal and current senior advisor with the Health Equity Thematic Network, will be taking over as interim Chair, effective from 5th September 2023. His appointment was made by the Governing Board during their May meeting. Jordi will serve in this role for a period of up to one year while a permanent Chair is recruited. The Governance and Nomination Committee will oversee the recruitment process and make a recommendation to the Board of Trustees.

Jordi’s tenure with Cochrane dates back to 1997 when he joined the Iberoamerican Cochrane Centre and contributed to the expansion of the Iberoamerican network. He has been part of the Lung Cancer group, the Equity Methods Group, Cochrane Canada and Cochrane Musculoskeletal, before joining the newly created Equity Thematic Network.

"I'm humbled by the opportunity to expand on the work that Tracey and Catherine have led to transform our organization. As we navigate into a new structure, I’m excited to explore the opportunities that a move to open access could bring to Cochrane and the world. I’m looking forward to working with our talented community to grow our reach and impact.”

- Jordi Pardo Pardo

Catherine Spencer, Cochrane CEO, extended a warm welcome to Jordi as interim Chair observing: “Jordi Pardo Pardo has an excellent understanding of both the workings of the Governing Board and the purpose of Cochrane. His appointment is welcomed by the Central Executive Team to ensure continuity as Catherine Marshall and Tracey Howe’s time comes to a close.”

She further expressed sincere gratitude to Catherine and Tracey for their unwavering dedication, leadership and invaluable contributions to Cochrane while wishing them all the best in their future endeavours.

• Learn more about Cochrane's governance and management

Tuesday, August 22, 2023

Specifications: Permanent – Full Time
Salary:  £60,000 per Annum (1.0 FTE)
Location: Remote – UK Based
Closing date: 04 September 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Head of Editorial Policy and Research Integrity is responsible for Cochrane’s editorial policies and research integrity and methods standards. They will ensure Cochrane’s review production processes and systems support efficient and trusted review production, with a focus on improving author experience. This role involves editorial and operational leadership, working closely with colleagues across the Evidence Production & Methods and Publishing and Technology directorates to ensure Cochrane’s product development aligns with its strategic priorities.   

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive on boarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 04th Sep, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, August 21, 2023 Category: Jobs

Monday, August 21, 2023

中用量の吸入ステロイド薬でコントロール不良な喘息に推奨される治療選択肢 要点 • 中用量の吸入ステロイド薬（ICS）に長時間作用性β2刺激薬（LABA）または長時間作用性抗コリン薬（LAMA）を追加すると、経口ステロイド薬による治療を要する喘息発作が減少する可能性が高い。またICS単独と比較して、良好な症状コントロールのオッズ（達成確率）が増加するが、ICSの用量を2倍にしても、おそらく増加しない。LAMAよりもLABAの方がはるかに多くのデータが見つかった。 • 包含された研究の実施期間は平均わずか6か月であったため、高用量ICSの長期的な副作用について、さらに研究が必要である。ステロイドによる副作用を最小限に抑えるために、ICSは最小有効量で使用することが推奨される。 喘息とは何か、またどのように治療するのか 喘息とは、気道の炎症と狭窄（細く狭くなること）を特徴とする慢性呼吸器疾患であり、喘鳴（ぜんめい）、咳、胸の圧迫感、息切れなどの症状を引き起こす。治療には、発作治療薬（短時間作用性気管支拡張薬など）や必要に応じて発作予防薬（ICSなど）の吸入薬を使用するほか、発作の誘因を避け、健康的な生活習慣を維持することが必要である。 知りたかったこと この研究では、中用量のICSで喘息を上手くコントロールできていない10代および成人を対象に、喘息コントロールを改善するのに最適な方法を...

視機能、黄斑（目の奥の部位）の保護、および睡眠の質の向上のためのブルーライトフィルター付き眼鏡レンズ 本レビューの目的は何か？ 本レビューの目的は、ブルーライトカットレンズとしても知られるブルーライトフィルター付き眼鏡レンズが、視機能、黄斑の保護、および睡眠の質に与え得る利益と安全性について調査することである。本レビューの著者らは、関連するすべての研究を収集、分析し、入手可能な最良のエビデンスをまとめた。 要点 ブルーライトフィルター付きレンズは、通常のレンズと比較して、コンピューター作業による短期的な眼精疲労の軽減には差がない可能性がある。潜在的な有害作用は一時的で、一般的に軽度であり、そのほとんどはレンズ自体よりも、眼鏡全般に関連していると考えられる。 矯正視力（最高矯正視力）、濃淡や模様の違いを識別する能力（コントラスト感度）、色識別、明るい光によるまぶしさ（不快グレア）の軽減、目の奥の網膜（黄斑）の健康状態、睡眠の状態（血中メラトニン濃度や睡眠の質など）、および使用者の満足度など、視機能と睡眠における多くの側面に対するブルーライトフィルター付きレンズの効果についてのエビデンスを得るためには、今後のさらなる研究が必要である。 本レビューでは何が調査されたのか？ 主要評価項目は、1か月以上レンズを使用した後に測定された眼精疲労の自覚的および定量的な評価における変化であり、その...

In healthcare, evidence-based information serves as the cornerstone of informed decision-making. Yet, the true impact of this knowledge lies in its accessibility and comprehensibility. Recognizing this, Cochrane China is running it's third annual competition that hopes to boost public interest in Cochrane reviews and fosters inventive pathways for sharing knowledge.

At the forefront of this endeavour is the Centre for Evidence-based Chinese Medicine at Beijing University of Chinese Medicine, a Cochrane China Network Affiliate that acts at the Translation and Dissemination Working Group. This Working Group, in collaboration with the Centre for Evidence-based Chinese Medicine of Beijing University of Chinese Medicine, the Cochrane China Network Affiliate acts as the Translation and Dissemination Working Group. This working group is jointly hosting the competition with the Center for Evidence-Based and Translational Medicine at Wuhan University, the Second School of Clinical Medicine at Wuhan University, and the dedicated members of the Cochrane China community.

Cochrane defines knowledge translation (KT) as the process of supporting the use of health evidence from our high-quality, trusted Cochrane reviews by those who need it to make health decisions. KT helps to make Cochrane evidence accessible and useful to everybody while advocating for evidence-informed health care.

We welcome you to submit a KT piece to this competition! 

Simplified Chinese: Submissions need to be in Simplified Chinese. If you start in a different language, you can always translate it. It is helpful if one person in your team can communicate in Simplified Chinese as most communication by organizations around the competition will be in this language. 
Open to all: All ages and geographical locations are welcome to enter.
Get creative: A wide range of creative formats is welcome;  past winners include pictures, written work, and videos. Some previous examples include this stop-motion video and these infographics.
Unite together: Participants can choose to submit their work either as individuals or as part of a team, allowing for diverse and collaborative contributions.
Deadline: The deadline for submissions is 30 August 2023. 
Winners: Winning submissions will be featured on the WeChat public website and the BUCM Essential Perspectives on Evidence-Based Medicine video channel. There are also branded prizes to be won!
Get in touch: Find out more information or  ask questions at ebmvolunteer@163.com

Join the WeChat account for more information: 

Monday, August 21, 2023

男性不妊でないカップルの体外受精における顕微授精と一般体外受精との比較 テーマ 体外受精（IVF）中の卵子受精において、総精子数と運動率が正常な男性を持つカップルを対象に、顕微授精（卵細胞質内精子注入法、ICSI）と従来の体外受精（c-IVF）を比較した。 レビューの論点 総精子数と運動率が正常な男性を持つカップルにおける顕微授精と従来の体外受精の効果に関するエビデンスをレビューした。 背景 40年以上前に開始されて以来、体外受精は不妊治療の礎となっている。体外受精の過程では、卵巣を過剰に刺激して複数の卵子を採取する。従来の体外受精の場合、卵子は実験室で精子と一緒に培養され、受精するかどうか待たれる。もともと1992年に発見された顕微授精は、精子の数が少ないことを克服するための受精技術として導入された。顕微授精は現在、体外受精の追加治療としても用いられ、従来の体外受精で受精率が低かったり、完全に受精しなかったりした症例や、軽度の男性不妊症、あるいは原因不明の不妊症の場合にも利用されている。顕微授精が従来の体外受精と比較してより好ましい結果をもたらすかどうかを比較した。 研究の特徴 本レビューは、不妊治療を受けた計1,539組のカップルを対象として、顕微授精と従来の体外受精を比較した3件のランダム化比較試験（RCT）を含んでいる。エビデンスは2023年2月現在のものである。 主な結...

Cochrane UK is gearing up to host the much-anticipated Cochrane Colloquium at London's Queen Elizabeth II Centre (QEII) from September 4th to 6th, 2023. The event promises an enriching experience, combining learning, networking, and fun. The countdown has begun, but there is still time to register!  

On Wednesday, September 6th, during the lunch break, join us for the #CochraneLondon Library of People. This event offers a unique opportunity to engage in conversations with human 'books,' who possess rich life experiences to share. This informal and enjoyable setup offers a refreshing way to connect with others and gain fresh viewpoints.

At the Library of People, you can "borrow" individuals as if they were open books, delving into their narratives and have conversations about subjects that intrigue you. These interactions will take place within small groups, enabling meaningful discussions. Each "book" will come with a list of suggested questions to facilitate the conversation's outset. 

The Cochrane Book Club members will be your "Librarians," guiding you in the selection and discovery of your ideal "book". You'll encounter a rich variety of "books," representing diverse nationalities, various career stages, roles within the Cochrane community, and personal passions.

Mentee to Mentor - crossing continents Omolola Alade 

15,000km southeast of home (Ibadan, Nigeria) I was first introduced to evidence synthesis during a graduate course on Epidemiology at the University of Sydney, Australia. I struggled with homesickness, but distracted myself by interpreting forest plots and critical appraisals of systematic reviews.

Several years later, this time 10,000km northwest of home, having mastered homesickness, I became a mentee of the US Cochrane network. Working with mentors moved me from my distant, hesitant interest to being an active contributor to evidence synthesis. Now I am leading a research project, with seven other mentees, on equity considerations in mentoring programs for evidence synthesis.

Back home in Nigeria, I am part of an inaugural collaborative initiative between my faculty and the Nigerian Institute of Medical Research to conduct several systematic reviews on oral health. I am also a mentor to the next generation of oral health researchers in evidence synthesis, mentoring three researchers in the first cohort of the National Oral Health for Development programme of the Nigerian Institute of Medical Research. So, as you can see I have gone from mentee to mentor as I have travelled the world.

 

Translating best evidence to support disaster settings - Evidence Aid (born in Cochrane in 2004) Claire Allen

Like many others I sat transfixed by the dreadful events which unfolded on 26 December 2004 in the wake of the Indian ocean earthquake and tsunami. Like many others, I had no idea what we as a society, or indeed Cochrane (which I’d worked with since 1997), could do, apart from giving money. Thankfully Mike Clarke who was Chair of the Board of Trustees in Cochrane and other colleagues had the inspired idea that as an organisation, Cochrane was perfectly placed to provide robust information to help those who were supporting the relief effort in making their decisions. And, boom, Evidence Aid was born. I jumped ship from Cochrane to Evidence Aid formally in 2014. From then, Evidence Aid became an independent charity, working with many organisations such as Save the Children, the Pan American Health Organization, the World Health Organization and we were at the forefront of the information provision when the recent Covid pandemic hit the world, starting our efforts in February 2020, before lockdowns were started.

 

My experience as an early career professional and Cochrane Ana Beatriz Pizarro

I am a 25-year-old early career registered nurse hailing from a small town in the north of Colombia. As a first-generation college student, I take immense pride in being the youngest editorial board member representing The Early Career Professionals Group. My passion for evidence-based healthcare is reflected in my extensive work, having published over 30 systematic reviews.

My primary goal is to improve lives in the Global South through multidisciplinary approaches, understanding specific health-disease problems, their impact, and potential applications in public health.

Beyond my professional pursuits, diverse interests add colour to my life, including singing, playing the ukulele, watching films, and finding joy in going to the beach and outdoor running.

I believe in the power of stories and have experienced their impact firsthand in my life. As a 'book' in the #CochraneLondon Library of People, I am eager to engage in conversations and share my life experiences, professional insights, and personal interests.

What have Hogwarts and Sherlock Holmes got to do with teaching EBM? Maria Björklund

I am a librarian at Cochrane Sweden who loves to read. Fantasy and detective stories are my favourite genres and I always enjoy how libraries and librarians are represented in fantasy and detective fiction!  I also am drawn in by how a mystery unfolds and you pick up clues and evidence (of course!) along the way and try to solve the crime or mystery yourself while reading.

I teach evidence-based medicine and refer to Sherlock Holmes and fictional libraries (like Hogwarts) when I am helping students understand evidence-based medicine and systematic data retrieval - it is a successful and engaging tactic.

 So, my reading preferences are sometimes also reflected in my professional work, and I think it is a nice way of engaging students in evidence- based medicine.

 A life-changing treatment decision: hope, fear and a bit of evidence? Sarah Chapman

I’ve had progressive hearing loss throughout my adult life and had got to the point where I was struggling to hear, despite hearing aids. In 2021, I was offered a potentially life-changing treatment, a cochlear implant. This would involve surgery and an irreversible process in which the ‘normal’ mechanism of hearing would be destroyed. People meeting the criteria for a cochlear implant are likely to benefit, but outcomes aren’t guaranteed and whether, how much, and in what ways I would benefit were uncertain. I learned first-hand that how we make treatment decisions in our real, messy lives doesn’t necessarily fit the neat models we see when we read about evidence-based decision-making.

Wikipedia: the world largest encyclopaedia - friend or foe? Jennifer Dawson

Communicating and sharing high-quality and reliable evidence informed information is a passion of mine. I have been working with Cochrane as our Wikipedian-in-Residence since 2016. The viewership of medical articles on English-language Wikipedia alone surpasses 2 billion page views per year and there are about 40,000 articles that relate to human health. 

In 2021, viewership of the main Wikipedia COVID-19-related article was over 500,000 views a month, far more than most of the other sources of information on the internet. Medical content is also available in over 280 languages. 

When I tell colleagues in my field that I help improve medical articles on Wikipedia, I usually get all sorts of interesting questions (and sometimes funny looks)! Why should we be considering Wikipedia? Do you recommend Wikipedia as a resource for people with questions about their health? How hard is it to edit Wikipedia? Many people in medical and evidence-based medicine fields find Wikipedia very frustrating. They are not wrong! There are many, many, articles that need improving and many that share incorrect, missing, or outdated information. It can be hard to jump in as a new editor and navigate conflict of interest and work with a very keen volunteer community of often anonymous editors. Rather than dismiss the ‘World’s Largest Encyclopedia’, why not learn more and potentially help improve what people are accessing!

Careless comms costs lives: battling misinformation on statins Harry Dayantis

 

There are few scientific topics as needlessly controversial as statins. These cholesterol-lowering drugs are prescribed to millions of people worldwide and have underdone countless trials evaluating their benefits and risks. There is an overwhelming scientific consensus that they reduce the risk of heart disease. So why do people get so worked up about them, and why do I care?

I care because my father died of a sudden heart attack overnight when I was at university. He was 49 years old and held national records for long-distance running. The post-mortem revealed that he had heart disease, and he might still be alive today if he’d been diagnosed and treated with statins. The risk has a significant genetic component, and I now take statins myself.

I’ve been involved in communicating many research papers on statins over the past decade, at UCL and Oxford University. I’ve worked with cardiologists and researchers to share the real evidence on statins in an often hostile media environment. It’s important that benefits and harms are communicated accurately so that people can make informed decisions; there is evidence that media scare stories have prevented many people from taking statins, potentially costing thousands of lives.

Accessibility at conferences shouldn’t just be a tick box Emily Messina

Attending or presenting at conferences is often an essential aspect of academic careers. We can share research and network, but let’s be honest, how many of us are mentally exhausted just planning to attend a conference, let alone after its over? Despite the fact that many of us, around 20%, are D/deaf, hard-of-hearing, disabled, and/or neurodivergent, we continue to leave accessibility as an afterthought. We strain to read slides or posters with tiny print, struggle with noise and sensory overload in crowded poster halls, forced to spend energy hunting for accessible paths through the conference space, and miss information that is only presented orally. Aren’t we tired of bare knuckling our way through conferences? Without creating content that's accessible, how can we have our science received, understood, and (importantly) acted on. So, let’s talk, share our experiences, and we can learn from each other better ways to improve accessibility and share our research more effectively.

Storytelling to break down boundaries Wanjiru Mwangi

Step into my world of communications and let me take you on an exciting journey about storytelling and the boundaries it breaks. Since time immemorial, storytelling has been a fundamental part of human connection. And in research, it has helped transcend the rigid confines of data and facts, transforming them into narratives that resonate with human emotions and experiences. Not by distorting truths or oversimplifying the complexities of research, but by transforming the most complex ideas into accessible information for those who truly need or yearn to grasp it. As you read through this, try and imagine the power of a personal story, a memory that resonates deeply, or a song that touches your heart. These diverse mediums of storytelling can foster deeper connections between researchers and their audience, leading to a more informed and enlightened public. So come chat with me, Wanjiru, a communications expert in both internal and external communications.

 Don't miss out on this exhilarating opportunity to engage with living stories. No pre-registration for Colloquium attendees is required; simply join us on the event day!

Library of People: Connecting Through Stories
Wednesday, September 6th
1:00 pm - 2:00 pm
Level 1, Pickwick

In addition to this Library of People event, we invite you to bring used books to Level 1 throughout the event. There will be a free book exchange table where you can pick up your next great read! 

Find out more about the Colloquium:

• View and update your schedule
• Visit the Colloquium website
• ‘Take a break' activities

Get in touch: colloquium@cochrane.org

Thursday, August 17, 2023

Friday, August 11, 2023

呼吸器を使用し、脳出血のリスクがある未熟児の痛みや不快感に対処する薬剤 レビューの論点 痛み止め（鎮痛薬）は、正期産（訳注：37週0日～41週6日）よりも早く生まれて（「早産児」）機械的な呼吸補助を必要とする赤ちゃんの脳出血や死亡を減らし、長期的な発達を改善するか 背景 早産児、特に妊娠28週よりも前に生まれた赤ちゃんは、時に脳出血を起こすことがある。脳の出血が重度でなければ、赤ちゃんは完全に回復するか、のちに問題があっても軽度で済むかもしれない。出血が重篤になると死亡するか、のちにいくつか問題が生じる可能性がある。現在のところ、脳出血を予防したり治療したりする対処方法はない。 実施したこと 早産児の脳出血予防のための鎮痛薬を検討したコクラン・レビューを検索した。各レビューの質を評価し、その結果を要約することによって、各治療薬に関連する現在のエビデンスを一か所に集めた。 わかったこと コクラン・レビュー7件とコクラン・レビューのプロトコール（計画書）1件を対象とした。2件のレビューには、対象外の範囲の研究が含まれていた。たとえば、妊娠末期に普通に生まれた赤ちゃんや、呼吸器を必要としない赤ちゃんに焦点を当てたものなどである。それ以外の5件では、パラセタモール（3件）、ミダゾラム（3件）、フェノバルビタール（9件）、オピオイド（20件）、イブプロフェン（5件）が検討されていた。 主な...

運動ニューロン疾患として知られる筋萎縮性側索硬化症の患者における経腸経管栄養 要点 筋萎縮性側索硬化症（ALS）患者において、経管栄養の使用と経口栄養の継続を比較した、または、異なる種類や方法における栄養チューブ留置の安全性とタイミングを調査したランダム化または準ランダム化（部分ランダム化）比較試験は見つからなかった。ALSは運動ニューロン疾患（MND）の最も一般的な病態であり、この2つの用語はしばしば同じ意味で使われる。 ランダム化試験および準ランダム化試験は、参加者のグループにおける類似性を保証することを目的とした試験である。このような研究は、栄養チューブの挿入が経口栄養の継続と比較して生存期間を延長し、生活の質を改善するかどうかについて、臨床家やALS患者に情報を提供することができる。しかし、質の高いエビデンスがないにもかかわらず、国際的な専門家のコンセンサスやガイドラインがALS患者への経管栄養を支持しているため、このような試験を実施するには倫理的な問題がある。 ALSとは？ ALSは、運動を司る神経が機能しなくなる病気である。ALSは衰弱を引き起こし、麻痺の状態になるまで時間の経過とともに悪化する。それは、ほとんどの場合が命に関わるものである。 ALS患者のほとんどが嚥下障害を発症する。これらは深刻な体重減少を引き起こし、患者は食べ物や飲み物を気管に吸い込む危険性がある...

Specifications:  Fixed term maternity leave cover (through May 2024)
Salary: £43,000 Pro-rated 0.6 FTE (though 0.4 FTE will be considered)
Location: Remote - Candidates from the UK, Germany and Denmark with fixed-term employment contract. Candidates from the rest of the world with fixed-term consultancy contract.
Closing date: 20 Aug 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world.” Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into five directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Learning and Support Officer will play a central role in revising and updating the Learning Team’s portfolio of author training materials, as Cochrane methods and processes change and evolve over the coming months. The Learning and Support Officer will also coordinate activities of the Cochrane Trainers’ Network, including communicating with the Network about updates to training materials and organizing train the trainers’ sessions for trainers from across the Cochrane Community. Given the geographically dispersed nature of Cochrane authors and trainers, this learning and support will be delivered remotely.

This role is part of the Learning Team, which is responsible for providing learning materials and training for Cochrane staff, authors, and users of Cochrane evidence. The team sits within the wider Membership, Learning and Support team, which strives to ensure that Cochrane recruits, develops and retains high quality contributors to participate in our work by providing a comprehensive service to engage new contributors, reward and develop existing contributors and support all members of our community when they need help.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here.
• The deadline to receive your application is 20th Aug, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, August 7, 2023 Category: Jobs

経鼻カニューレによる高流量酸素療法による新生児の呼吸補助 レビューの論点 経鼻カニューレによる高流量酸素療法は、呼吸のサポートを必要とする重症新生児の健康転帰を改善するか？ 背景 新生児が呼吸困難に陥った場合、肺に空気を出し入れする（換気）ために外部からの呼吸サポートが必要になることがある。この呼吸のサポートにはさまざまな方法がある。侵襲的人工呼吸では、赤ちゃんの気管にチューブを挿入して空気を送り込む。非侵襲的人工呼吸では、口や顔に装着するマスクや、鼻孔のすぐ内側に装着する小さなチューブを介して空気を送り込む。これらの方法は、侵襲的人工呼吸に伴う合併症のいくつかを避けることができるため、しばしば好んで用いられる。 高流量経鼻カニューレ(HFNC)酸素療法とは何か？ HFNC酸素療法は、非侵襲的呼吸補助の1つである。これは、加温、加湿された酸素ガスを、鼻孔のすぐ内側に配置されたチューブを介して、毎分2リットル以上の流量で供給するもので、他の酸素療法よりも優れた効果をもたらすと提案されている。しかし、生後1か月（新生児期）の正期産児（妊娠37週以降に出生した児）においては、HFNCの安全性と有効性に関するエビデンスは限られており、この集団での使用に関する意見の一致はみられない。 知りたかったこと 高流量経鼻カニューレ酸素療法が、他の非侵襲的支援方法と比較して、生後1か月間に呼吸補助を...

Cochrane UK is gearing up to host the much-anticipated Cochrane Colloquium at London's Queen Elizabeth II Centre (QEII) from September 4th to 6th, 2023. The event promises an enriching experience, combining learning, networking, and fun. The countdown has begun, but there is still time to register  

To ensure you make the most out of the Colloquium, we've gathered a selection of insights and suggestions from members of the Cochrane Community. These tips will guide you through multiple days of intense engagement, helping you maintain your well-being, enthusiasm, and collaborative spirit throughout the event. Have other suggestions? Let us know by using the hashtag #CochraneLondon on social media. 

1. Download a Business Card App

Embrace the digital age by adopting a digital business card app. This eco-friendly option enables you to effortlessly exchange contact information, fostering future collaborations.  

"When Cochrane recently attended the 76th World Health Assembly we used blinq.me digital business cards. It was free, easy to set up, and was the main form of business cards that people were using. I hope our Cochrane Community embraces digital business cards as an environmentally conscious choice and helps sets themselves up for future collaborations."

- Catherine Spencer, Cochrane CEO

2. Plan your routes with the Citymapper App

The Colloquium venue is a short walk from tube stations, many hotels, and much more.  The Citymapper app (free) is a really useful tool offering offline navigation to help you get around, including walking, bus, tube and rail routes, ensuring you always know where you’re headed.

" Even as a UK local, I use the Citymapper app and recommend it to anyone coming to London. It can provide accessible route information which is also helpful if you have luggage with you, has live tube and bus information, and is perfect for walking around and exploring without wifi. London has so many great spots to visit before and after the Colloquium - including the Bartholomew Fair events - and I hope having this app will give you the confidence to go out and explore! ”

- Sarah Chapman, Cochrane UK

3. Pack your walking shoes for the Anne Anderson Walk

The Anne Anderson Walk is about 4.5km long and can be completed at your own pace. It will take you past some of the city's most iconic landmarks, give you stunning views of London, and educate you about close-by historical and medical points of interest. Be sure to bring comfortable walking shoes and take advantage of the opportunity to explore London's surroundings while connecting with fellow attendees.

"As the recipient of the 2021 Anne Anderson Award, this walk holds a special place in my heart. It's also a cherished highlight for many Colloquium attendees. While conferences often keep you indoors, the Anne Anderson Walk ensures you truly experience the location. This year, the venue is surrounded by historical sites that showcase London's medical legacy and the significant role of women. Don't forget to bring your walking shoes, contribute to the Anne Anderson Award, and prepare yourself for an enriching experience!"

- Jackie Ho, Cochrane Malaysia

4. Get your official #CochraneLondon merchandise from the Cochrane Store

Select and purchase your limited-edition #CochraneLondon items beforehand. The print-on-demand store offers an exciting range of items, including tote bags, t-shirts, and mugs, which you can choose to purchase for use during the conference or as cherished souvenirs of the event. Please note that these items will not be available for purchase at the Colloquium itself and must be acquired in advance.

"Cochrane is prioritizing sustainability and the environment with this event. Rather than traditional conference swag bags of items you'll never use again, we've taken an eco-conscious route by introducing a print-on-demand store. This not only reduces unnecessary waste but also ensures that participants receive merchandise they truly value and intend to use. I love my Cochrane t-shirt and mug and am excited to see the new items added to the store!  Alongside #CochraneLondon items, there are also ones to celebrate Cochrane's 30th Anniversary items, as we will be celebrating this milestone at the colloquium."

- Sabrina Khamissa, UK

5.  Use the #BetterPoster and #BetterPresentation templates
We worked with the leading research team investigating the accessibility of presentations at academic conferences to create templates for those presenting a poster or doing an oral presentation. Both presenters and attendees will benefit from the use of these templates! 

"I love how evidence-based Cochrane is in so many aspects of their work. Based on the latest research, #CochraneLondon templates makes creating posters and PowerPoint slides so much easier. By adopting these templates, researchers can elevate the impact of their findings, facilitate knowledge transfer, and foster inclusivity within academic conferences. It's going to be exciting to attend a Colloquium with so many using them; attendees will be able to swiftly identify the presentations that align with their interests and it will make it easier for those of us who have English as a second language."

-  Xun Li, Cochrane China

6. Explore the full programme and curate your own Colloquium experience 

Take the time to look through the full Colloquium programme and plan your schedule. Immerse yourself in a captivating lineup of plenary talks, workshops, posters, oral presentations, and meetings that encompass a vast spectrum of topics and issues in evidence-based health care. You can personalize your experience to match your interests and goals!

"The Cochrane Colloquium is more than just a typical academic gathering! It has posters, oral presentations, and a lineup of plenary talks but it goes beyond just academic content! Cochrane Colloquiums are also about building connections and creating unforgettable memories. Be sure to check out all the 'take a break' fun activities and the social gathering at the Natural History Museum!  I encourage all attendees to delve into the comprehensive programme and strike a balance between planned engagements, networking, and enjoyable moments."

- Andrea Moreno, Cochrane France

7. Unite and connect with fellow book lovers! 

Finished a book on the way to the Colloquium and want a new one for the trip home? Have piles of books that could use a loving home? Bring a book for the  #CochraneLondon book exchange! You can also 'sign out' a human book at our Library of People! 

"The love for books at Cochrane extends beyond the Cochrane handbooks! The Cochrane Book Club is hosting a book exchange at the Colloquium. Bring in a book, write your recommendation and a note on a bookmark, and leave with a new book! The book exchange is happening on level 1 over the three days. Book Club members will also be librarians at the Library of People happening in the same area on Wednesday at lunch. We're looking forward to connecting with you over some good books! "

-  Anne-Catherine Vanhove, Cochrane Belgium

8. Mix and Mingle! 
Beyond catching up with colleagues and friends, this event is an opportunity to engage with newcomers interested in our work and potential future collaborators. Embrace the chance to expand your network and foster meaningful connections that could shape exciting collaborations. Stay open to new encounters and the possibilities they bring!

"My best advice: meet and talk to as many people as you can. It's nice to meet colleagues, but everyone at the Colloquium will have an interest in Cochrane’s work and will welcome the chance to share their thoughts and ideas. They may be just the person you are looking for! For me, this approach has given me friends for life spread across the organisation."

-  Elizabeth Royle, UK 

9. Harness the power of social media

While we're meeting in-person, you can also embrace the digital buzz by actively using the event's hashtag; #CochraneLondon.  Through social media, you can connect with other attendees, follow up with presenters, and share your insights with your followers.  

  "You can get ready for Colloquium by sharing the fun badges on your social media to announce to everyone that you will be there! Also, look through the official #CochraneLondon Social Media Ambassadors and give some a follow. Once you're at the Colloquium, be sure to use the official #CochraneLondon hashtag and share your highlights! "

-  Georg Rüschemeyer, Cochrane Germany

10. Make your well-being a priority! 
Cochrane recognizes that conferences can be busy and overwhelming at times. We want to ensure that Cochrane London attendees have the opportunity to prioritize their well-being while also engaging in some fun and social activities. Some people take a break by connecting with others and some people need time to themselves - the colloquium offers space and activities to help meet both of these needs!

"My advice is to treat #CochraneLondon like a marathon, and not a sprint. Every day will be busy, filled with sessions to attend, and people to meet, and it’s important to make the most of this opportunity. But it’s also important to pace yourself and give yourself permission to schedule in proper breaks each day. Take time out for yourself in the Colloquium's 'Quiet Corner', go for the Anne Anderson Walk, or even take some time to go back to your hotel room - especially if it means you are then able to return to the main sessions refreshed and recharged! 

-  Nuala Livingstone, Northen Ireland

Have other suggestions and tips? Let us know by using the hashtag #CochraneLondon on social media.

As you embark on your Cochrane Colloquium journey, we hope that these valuable tips will equip you with the knowledge and confidence to make the most of this enriching experience. We are looking forward to welcoming you to London and uniting the community once again! Don't miss out on this transformative event, where trusted evidence takes centre stage and lasting connections flourish.

Find out more:

• View and update your schedule
• Visit the Colloquium website
• List of Plenary speakers
• Take a break activities
• The social event at the Natural History Museum
• The Anne Anderson walk

Get in touch: colloquium@cochrane.org

Thursday, August 17, 2023